
方冠宇,博士,特聘副教授,从事传统发酵食品中的微生物群落结构、功能及其适应性进化等方面研究。自2023年7月入职来主持国家自然科学基金项目1项,发表SCI/EI论文25篇。研究成果对推动传统发酵食品的生产技术创新、提升产品品质以及提高生产效率起到了一定作用。担任浙江省团队科技特派员首席专家,浙江省调味品协会理事,Food Quality and Safety、Modern Agriculture和Grain & Oil Science and Technology期刊青年编委,The ISME Journal、Journal of Environmental Sciences、Future Microbiology、Sustainable Microbiology、《食品工业科技》 等多个SCI / EI期刊的审稿人。
研究方向:
(1)传统发酵食品中微生物生态学(群落的组装、进化、互作)及其代谢潜能;
(2)利用基因组学和比较基因组学探究微生物生境适应性进化机制及代谢特征;
(3)解析病原微生物及其抗生素耐药性对人类健康风险和进化、传播机制研究。
主要科研项目:
[1] 国家自然科学基金青年项目(32401323),环境微生物在酿醋微生态系统中的适应性分子机制,2025年01月至2027年12月,30万元,主持
[2] 浙江农林大学人才启动项目(2024LFR050),氮源添加对黄酒品质影响的微生物学机制解析,2024.04-2027.03,15万元,主持。
[3] 国家重点研发计划项目(2024YFF1105500),粮食收储质量提升关键技术研究与产业化示范,2024年12月至2027年11月,2000万元,参与
发表的主要论文:
[1] Fang G-Y*, Mu X-J, Huang B-W, Jiang Y-J*. Monitoring longitudinal trends and assessment of the health risk of Shigella flexneri antimicrobial resistance[J]. Environmental Science & Technology, 2023, 57(12): 4971-4983. (中科院一区Top,IF5 years:11.6)
[2] Fang G-Y*, Wu F-H, Mu X-J, Jiang Y-J, Liu X-Q*. Monitoring longitudinal antimicrobial resistance trends of Staphylococcus aureus strains worldwide over the past 100 years to decipher its evolution and transmission[J]. Journal of Hazardous Materials, 2024, 465: 133136. (中科院一区Top,IF5 years:11.9)
[3] Fang G-Y*, Liu X-Q, Jiang Y-J, Mu X-J, Huang B-W. Horizontal gene transfer in activated sludge enhances microbial antimicrobial resistance and virulence[J]. Science of The Total Environment, 2024, 912: 168908. (中科院一区Top,IF5 years:8.6)
[4] Fang G-Y, Mu X-J, Huang B-W, Wu G-Z, Jiang Y-J*. Fungal biodiversity and interaction complexity were the important drivers of multifunctionality for flavor production in a spontaneously fermented vinegar[J]. Innovative Food Science & Emerging Technologies, 2023, 83: 103259. (中科院一区Top,IF5 years:6.5)
[5] Fang G-Y, Chai L-J*, Lu Z-M, Zhang X-J, Xu H-Y, Wang S-T, Shen C-H, Shi J-S, Xu Z-H*. Comparative genomics of Clostridium tyrobutyricum reveals signatures of environment-specific adaptation and metabolic potentials[J]. Food Bioscience, 2024, 61: 104691.(中科院一区Top,IF5 years:5.1)
[6] Fang G-Y, Chai L-J, Zhong X-Z, Jiang Y-J*. Deciphering the succession patterns of bacterial community and their correlations with environmental factors and flavor compounds during the fermentation of Zhejiang rosy vinegar[J]. International Journal of Food Microbiology, 2021, 341: 109070. (中科院一区Top,IF5 years:5.0)
[7] Fang G-Y*, Liu X-Q, Mu X-J, Huang B-W, Jiang Y-J. Distinct increase in antimicrobial resistance genes among Vibrio parahaemolyticus in recent decades worldwide[J]. Chemosphere, 2023, 340: 139905. (中科院二区Top,IF5 years:7.7)
[8] Fang G-Y, Chai L-J, Zhong X-Z, Lu Z-M, Zhang X-J, Wu L-H, Wang S-T, Shen C-H, Shi J-S, Xu Z-H*. Comparative genomics unveils the habitat adaptation and metabolic profiles of Clostridium in an artificial ecosystem for liquor production[J]. mSystems, 2022, 7(3): e00297-22. (中科院二区Top,IF5 years:6.1)
[9] Jiang J-J, Fang G-Y*, Wu C-L, Wang P, Zhang Y-Z, Zhang C, Wu F-H, Shan Z-C, Liu Q-R, Liu X-Q*. The Addition of Glutamine Enhances the Quality of Huangjiu by Modifying the Assembly and Metabolic Activities of Microorganisms during the Fermentation Process[J]. Foods, 2024, 13(17): 2833. (中科院二区,IF5 years:5.1)
[10] Qiu Z-Z, Wu F-H, Hu H, Guo J, Wu C-L, Wang P, Ling J-G, Cui Y, Ye J, Fang G-Y*, Liu X-Q*. Deciphering the Microbiological Mechanisms Underlying the Impact of Different Storage Conditions on Rice Grain Quality[J]. Foods, 2024, 13(2): 266. (中科院二区,IF5 years:5.1)
研究成果(奖项/专利/专著等):
[1] 一种机械搅拌法生产玫瑰醋的方法, 2020-11-10, 中国,ZL201810025250.9
[2] 一种黑枣露酒及其制备方法,2024-02-06,中国,ZL2010061197.5
[3] 一种固态发酵黑枣蒸馏酒及其制备方法,2023-09-19,中国,ZL202010800528.2
[4] 一种机械搅拌法生产玫瑰醋的设备,2018-11-13,中国,ZL201820042426.7
[5] 泵回流法生产玫瑰醋的设备,2018-11-13,中国,ZL 201820042323.0
教学工作:
参与本科生《食品微生物学》、《中国粮食》等课程教学,研究生《现代食品微生物》等课程教学
联系方式:
通讯地址:浙江省杭州市临安区武肃街666号浙江农林大学东湖校区,邮编311300
电子邮件: fangguanyu@zafu.edu.cn